Monteverde to Manuel Antonio is about 4 hours by road, depending on traffic, weather and your exact pickup and drop-off points. Both ends are away from the airports, so this is a town-to-town transfer rather than an airport run.
We found 4 Viator listings that name both Monteverde and Manuel Antonio and run in this direction (2 shared, 1 private, 1 other). Their stated journey times are 2 to 5 hours. Shared seats are normally priced per person; private transfers are normally priced for the whole vehicle or group. Each card below says which. Every listing includes pickup.
Manuel Antonio is built around the national park of the same name, with rainforest meeting beach, white-sand coves, sloths, monkeys, and Quepos just down the hill.
Vehicle types and specific amenities can vary by provider — check the booking listing before confirming.